2017

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04 February 2017

World Cancer Day 2017

We can. I can. That is the message that is spread during World Cancer Day, on 4 February. How can you – as a collective or as an individual – take action to reduce the global burden of cancer? The European Lead Factory currently has 34 programmes that focus on various targets related to cancer. In these programmes innovative approaches are used to find starting points for new drugs to fight this disease. 

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23 January 2017

Committed to strengthening the antibiotic arsenal

The European Lead Factory (ELF) is boosting the discovery of new drugs by making high throughput screening and a quality compound library available to academia and biotech’s. To be eligible, the proposed project has to meet certain conditions. For example, the project should be considered as innovative and it should be possible to optimize the associated assay for high throughput screening.

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19 January 2017

PDE4NPD and the European Lead Factory team up: parasite enzyme up for ultra-HTS against 450,000 compounds

With help of the European Lead Factory, the Phosphodiesterase Inhibitors for Neglected Parasitic Diseases (PDE4NPD) project takes the next step towards developing novel drugs against kinetoplastid parasites such as Trypanosoma brucei, the causative parasite of African sleeping sickness, and Trypanosoma cruzi, causing Chagas disease. Together, PDE4NPD and the EU Lead Factory will screen 450,000 compounds for their potential to inhibit one of the parasite PDEs the project has validated. 

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19 January 2017

A blueprint for public-private partnerships in early drug discovery

A recent review in Frontier in Medicine describes the outcomes and learnings of the first 3,5 years of European Lead Factory (ELF) operations. It gives an overview of the unique characteristics and results of the programme: ‘ELF enables breakthroughs in areas with unmet medical and societal needs, where no individual entity would be able to create a comparable impact in such a short time’.

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