This is a non exhaustive list of publications related to ELF work published in scientific journals. Please contact the programme office if you miss a relevant publication.
Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice
Synthesis and Structure‐Activity Relationships of N‐(4‐Benzamidino)‐Oxazolidinones: Potent and Selective Inhibitors of Kallikrein‐Related Peptidase 6
Elena De Vita, Niels Smits, Helma van den Hurk, Elizabeth M. Beck ,Joanne Hewitt, Gemma Baillie, Emily Russell, Andrew Pannifer, Véronique Hamon, Angus Morrison, Stuart P. McElroy, Philip Jones, Natalia A. Ignatenko, Nikolas Gunkel, Aubry K. Miller.
ChemMedChem, Volume 15, Issue 1: 79-95
doi: https://doi.org/10.1002/cmdc.201900536 January 7, 2020
Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1.
Beck, E.M.; Parnell, E.; Cowley, A.; Porter, A.; Gillespie, J.; Robinson, J.; Robinson, L.; Pannifer, A.D.; Hamon, V.; Jones, P.; Morrison, A.; McElroy, S.; Timmerman, M.; Rutjes, H.; Mahajan, P.; Wiejak, J.; Luchowska-Stańska, U.; Morgan, D.; Barker, G.; Rehmann, H.; Yarwood, S.J.
Cells 2019, 8, 1425
doi: https://doi.org/10.3390/cells8111425 12 November 2019
Diastereoselective Synthesis of Highly Substituted, Amino‐and Pyrrolidino‐Tetrahydrofurans as Lead‐Like Molecular Scaffolds
Steven M. Wales, Elena G. Merisor, Holly V. Adcock, Christopher A. Pearce, Ian R. Strutt, William Lewis, Daniel Hamza, Christopher J. Moody
Chemistry–A European Journal. 2018;24(32):8233-9.
doi: https://doi.org/10.1002/chem.201801046 2018 June 7
Translation of innovative chemistry into screening libraries: an exemplar partnership from the European Lead Factory
Polycyclic Sulfoximines as New Scaffolds for Drug Discovery
Mark L. G. Borst, Cécile M. J. Ouairy, Sander C. Fokkema, Alessandro Cecchi, Jessica M. C. A. Kerckhoffs, Vincent L. de Boer, Peter J. van den Boogaard, Rutger F. Bus, Rijko Ebens, Rob van der Hulst, Joop Knol, Rob Libbers, Zhou M. Lion, Bart W. Settels, Ellen de Wever, Khaled A. Attia, Piet-Jan Sinnema, Jesse M. de Gooijer, Karen Harkema, Marieke Hazewinkel, Susan Snijder, Kees Pouwer
ACS Comb. Sci. 2018;20(6):335-343
doi: 10.1021/acscombsci.7b00150 2018 May 1
Petasis/Diels‐Alder/Cyclization Cascade Reactions for the Generation of Scaffolds with Multiple Stereogenic Centers and Orthogonal Handles for Library Production
MicroScale Thermophoresis Sharpens Hit Triaging: European Lead Factory Combines HTS and a Biophysical Assay to Refine Early Drug Discovery
Realisation of small molecule libraries based on frameworks distantly related to natural products
Anthony Aimon, George Karageorgis, Jacob Masters, Mark Dow, Philip G. E. Craven, Martin Ohsten, Anthony Willaume, Rémy Morgentin, Nicolas Ruiz-Llamas, Hugues Lemoine, Tuomo Kalliokoski, Andrew J. Eatherton, Daniel J. Foley, Stephen P. Marsden, Adam Nelson
Organic & Biomolecular Chemistry 2018
doi: 10.1039/C8OB00688A 2018 April 11
Synthesis of Highly Substituted 1,2‐Diazetidin‐3‐ones, Small‐Ring Scaffolds for Drug Discovery
Marilia S. Santos, Andrew Nortcliffe, William Lewis, Tracey D. Bradshaw, Christopher J. Moody
Chemistry–A European Journal 2018;24(33):8325-8330
doi: https://doi.org/10.1002/chem.201801309 2018 March 31
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