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10 May 2016

Bridging the Innovation Gap

The European Lead Factory is described as ‘bridging the innovation gap’ in a recent Careers Feature in the journal Nature. 

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03 May 2016

First Spanish programme selected

The first drug target programme from Spain has been selected by The European Lead Factory. It involves an epigenetic target against cancer that is being investigated by the Center for Applied Medical Research (CIMA) at the University of Navarra.

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22 April 2016

Combinatorial library optimization process

The public part of Joint European Compound Library (JECL) is built using many small libraries (typically about 500 compounds per library) based around innovative scaffolds.

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20 April 2016

Thirty partners - four years together in the lead

European Lead Factory General Assembly 2016 in Leiden, The Netherlands

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01 April 2016

Nature Reviews Drug Discovery: ‘European Lead Factory hits its stride’

Today, Nature Reviews Drug Discovery published a News & Analysis article: ‘European Lead Factory hits its stride.’

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23 March 2016

IHL phase passes the thousand compounds mark for public programmes

Public target programmes that have received a promising Qualified Hit List (QHL) have the possibility to continue their collaboration with the European Lead Factory with the aim of producing an Improved Hit List (IHL). 

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27 January 2016

European Lead Factory has commenced a drug screening campaign for one of Effecta Pharma’s Dengue viral targets

"We are excited we can continue our initial collaboration with the EU Lead Factory and its European Screening Centre researchers in Oss, Oxford and  Newhouse, which has yielded a screenable assay for one of the critical Dengue virus proteins. Having the EU Lead Factory as part of our concerted effort to generate preclinical candidates for Dengue  is welcome support for Effecta and the patients suffering from this disease”, Effecta’s Directors Helmuth van Es and Paul Edwards said.

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22 January 2016

EU Lead Factory Early Career Researcher Event showcases novel ideas in Medicinal and Synthetic Chemistry in Barcelona, Spain

The European Lead Factory acknowledges the need for open exchange between researchers with different professional background and puts a focus on the career development of young scientists.

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21 December 2015

JECL sparks Drug Discovery community interest

Just one month after publication, the Drug Discovery Today article by Karawajczyk et al describing the quality of the JECL public compounds has reached Top 5 of the most downloaded articles of this prestigious journal.

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16 December 2015

The European Lead Factory has achieved significant milestones for 2015

400,000 novel drug-like compounds are now compiled in the Joint European Compound Library (JECL); and 60 drug targets have been selected for screening.

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