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23 February 2018

European Lead Factory wins Multiparty Collaboration award

On Thursday 22 February, the European Lead Factory (ELF) won the Multiparty Collaboration award at the Scottish Knowledge Exchange Awards ceremony 2018. This reward, organised by Interface, recognises and rewards the impacts achieved through collaborative academic and business partnerships. The ELF collaboration comprises 30 public and private partners from across Europe, including large pharmaceutical companies, SMEs, CROs and academic institutions.

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22 February 2018

ELF shows how it grows a portfolio for the future

The European Lead Factory has been continuously recruiting high quality target programmes over the past years. With a clear infographic, the European Lead Factory makes the process of growing its portfolio visible.

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20 February 2018

ELF use of the “hot” technique MST

The European Lead Factory (ELF) scientists are not shy of applying new techniques to deliver the best possible results. A recent perspective, published in SLAS Discovery, describes how getting hot (or not) can help in the triaging of primary HTS hits.

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06 February 2018

PhD thesis enhanced with ELF collaboration and compounds

On 30 January 2018, Stefan Baumeister defended his dissertation ‘Investigation of the properties of Acyl Protein Thioesterases and their role in Ras depalmitoylation’ at the Max Planck Institute of Molecular Physiology (MPI) in Dortmund. His thesis describes structural determinants for selectivity between two closely related enzymes. Specific inhibitors could be optimized thanks to compounds derived from Dr. Sonja Siever’s ELF programme. The new insights can prove important for understanding the role of these enzymes in the course of cancer. 

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31 January 2018

SciLifeLab signs Memorandum of Understanding

The SciLifeLab Director and the European Lead Factory executives of the European Screening Centre and the Public Chemistry Consortium have signed a Memorandum of Understanding for collaboration in future initiatives.

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10 January 2018

Oxford paper highlights JECL as good example of open science

The EU Lead Factory screening collection is assembled by and for both industry and public parties. This alternative innovation model is what the authors envision for the future.

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21 December 2017

European Lead Factory one of IMI’s most high-profile projects

Until now, the Innovative Medicines Initiative (IMI) has launched almost 100 projects to tackle the barriers that currently limit the efficiency, effectiveness and quality of medical research and drug development. 

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14 December 2017

The Research Network ELF experience

With six running target programmes, the virtual biotech The Research Network is unsurpassed in submitting interesting drug discovery programmes for screening by the European Lead Factory (ELF).

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12 December 2017

Joint European Compound Library >500 000 compounds

The European Lead Factory set out to assemble a screening collection of half a million compounds. Now, that ambitious goal has been reached. A truly pan-consortium achievement.

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11 December 2017

ELF sets screening record

During the lifetime of the European Lead Factory (ELF), both the number of screens performed per year and the size of the Joint European Compound Library have increased steadily. 

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