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19 October 2017

Top-level library design from University of York

Dr Will Unsworth, a talented young group leader at the Department of Chemistry, University of York, has been awarded the highest monetary incentive for the library he designed based on cyclic peptide mimetics.

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06 October 2017

Prix Galien to ELF scientist

Dr Mario van der Stelt, University of Leiden, has been awarded the prestigious Dutch Prix Galien Research Award (Galenus Researchprijs Nederland).

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04 October 2017

Five months project extension

In agreement with the European Lead Factory partners, the Innovative Medicines Initiative (IMI) has agreed with a no-cost extension of the term of the ELF project to the end of May 2018.

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22 September 2017

Successful screen for innovative depression and pain target

Having discovered an interesting protein involved in depression and pain, Dr Patrick McHugh, University of Huddersfield, wanted to access chemical tools to further explore its role and action.

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29 June 2017

>100 public qualified hits

Every year since 2015, around 50,000 public compounds, designed and synthesized by the European Lead Factory chemistry partners, have been added to the ELF screening collection the Joint European Compound Library.

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19 June 2017

ChemPass receives the highest monetary award from the European Lead Factory

Any European researcher can submit a design proposal of a chemical library that can be synthesised by the European Lead Factory and can subsequently be incorporated in the Joint European Compound Library (JECL). The project Library Design Committee rates the designs on six scientific criteria and determines the technical maturity level of the proposals. Budapest-based ChemPass ltd rose to the challenge and recently received the highest monetary award of 5.000 Euros for their library design proposal.

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24 May 2017

French biotech receives Qualified Hit List

The French biotech company CELLIPSE has taken the next step towards novel treatments for leukaemia patients thanks to the European Lead Factory.

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28 April 2017

Hitting the targets – Inspiring Stakeholder Meeting

On the 25-26 April the European Lead Factory (ELF) Stakeholder Meeting and 5th General Assembly took place close to Heathrow/Windsor, UK. With an exciting agenda focussing on four years of successful collaboration, the impact of the European Lead Factory and the future of drug discovery, the meeting was considered a great success by all participants.

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15 March 2017

Over 1,000 library proposals submitted to ELF

The European Lead Factory recently reached the milestone of having received over 1,000 library proposals for consideration.  These proposals have been considered by its Library Selection Committee, leading to the approval of 627 library designs for synthetic validation.

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08 March 2017

Virtual biotech company launched to battle Parkinson’s

In a world-first type of collaboration, Parkinson’s UK and the University of Sheffield have launched a joint venture biotech company, Keapstone Therapeutics. Parkinson’s UK has allocated 1 million GBP over the next sixteen months to further develop compounds that boost the internal cellular defence mechanisms against oxidative stress. These compounds were discovered by IMI’s European Lead Factory.

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