Publications

This is a non exhaustive list of publications related to ELF work published in scientific journals. Please contact the programme office if you miss a relevant publication. 
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09 July 2015

Facile Access to a Heterocyclic, sp3-Rich Chemical Scaffold via a Tandem Condensation/ Intramolecular Nitrone-Alkene [3+2] Cycloaddition Strategy

M. J. Rawling, T. E. Storr, W. A. Bawazir, S. J. Cully, W. Lewis, M. S. I. T. Makki,  I. R. Strutt, G. Jones, D. Hamza and R. A. Stockman
Chem. Commun., 2015, 51, 12867-12870
doi: 10.1039/C5CC05070G Epub 2015 Jul 9

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19 June 2015

Exploitation of the Ugi–Joullié Reaction in the Synthesis of Libraries of Drug-Like Bicyclic Hydantoins

J.D. Firth, R. Zhang, R. Morgentin, R. Guilleux, T. Kalliokoski, S. Warriner, R. Foster, S.P. Marsden, A. Nelson
Synthesis 2015; 47(16): 2391-2406
doi: 10.1055/s-0034-1378704 Epub 2015 Jun 19

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01 June 2015

Bioorganic & Medicinal Chemistry Symposium-in-Print

special issue on innovation approaches to the design and synthesis of small molecule libraries, with 13 contributions from ELF consortium partners.

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10 April 2015

Synthesis of a hexahydropyrrolo indole (HPI) compound library

Nickel S, Nickel P, Hellmert M, Ernst S, Jewell R, Pearce CA, Jones G, Hamza D, Kaiser M.
Bioorg Med Chem. 2015 Jun 1;23(11):2636-45. 
doi: 10.1016/j.bmc.2015.04.003. Epub 2015 Apr 10.

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31 March 2015

Efficient Isocyanide-less Isocyanide-Based Multicomponent Reactions

C. G. Neochoritis, S. Stotani, B. Mishra and A. Dömling
Org. Lett., 2015, 17 (8), pp 2002–2005
doi: 10.1021/acs.orglett.5b00759 Epub 2015 Mar 31

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28 February 2015

Innovative approaches to the design and synthesis of small molecule libraries

Nelson A, Roche D. 
Bioorg Med Chem. 2015 Jun 1;23(11):2613. 
doi: 10.1016/j.bmc.2015.02.046. Epub 2015 Feb 28.

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11 February 2015

Aminomethylhydroxylation of alkenes: Exploitation in the synthesis of scaffolds for small molecule libraries

Colomer I, Adeniji O, Burslem GM, Craven P, Rasmussen MO, Willaume A, Kalliokoski T, Foster R, Marsden SP, Nelson A.
Bioorg Med Chem. 2015 Jun 1;23(11):2736-40. 
doi: 10.1016/j.bmc.2015.01.058. Epub 2015 Feb 11.

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03 February 2015

Design and synthesis of 1,1-disubstituted-1-silacycloalkane-based compound libraries.

Ortega R, Sanchez-Quesada J, Lorenz C, Dolega G, Karawajczyk A, Sanz M, Showell G, Giordanetto F. 
Bioorg Med Chem. 2015 Jun 1;23(11):2716-20. 
doi: 10.1016/j.bmc.2015.01.046. Epub 2015 Feb 3.

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31 January 2015

Synthesis of 1,4,5 trisubstituted γ-lactams via a 3-component cascade reaction

Petersen MÅ, Mortensen MA, Cohrt AE, Petersen R, Wu P, Fleury-Brégeot N, Morgentin R, Lardy C, Nielsen TE, Clausen MH.
Bioorg Med Chem. 2015 Jun 1;23(11):2695-8. 
doi: 10.1016/j.bmc.2015.01.041. Epub 2015 Jan 31.

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31 January 2015

Cyclopentitol as a scaffold for a natural product-like compound library for drug discovery.

Padwal JD, Filippov DV, Narhe BD, Aertssen S, Beuving RJ, Benningshof JC, van der Marel GA, Overkleeft HS, van der Stelt M.
Bioorg Med Chem. 2015 Jun 1;23(11):2650-5. 
doi: 10.1016/j.bmc.2015.01.040. Epub 2015 Jan 31.

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