Publications

This is a non exhaustive list of publications related to ELF work published in scientific journals. Please contact the programme office if you miss a relevant publication. 

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31 January 2015

Synthesis of hexahydropyrrolo[2,1-a]isoquinoline compound libraries through a Pictet-Spengler cyclization/metal-catalyzed cross coupling/amidation sequence

Petersen R, Cohrt AE, Petersen MÅ, Wu P, Clausen MH, Nielsen TE.
Bioorg Med Chem. 2015 Jun 1;23(11):2646-9. 
doi: 10.1016/j.bmc.2015.01.039. Epub 2015 Jan 31.

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17 January 2015

Stereoselective synthesis of a natural product inspired tetrahydroindolo[2,3-a]-quinolizine compound library.

Sankar MG, Mantilli L, Bull J, Giordanetto F, Bauer JO, Strohmann C, Waldmann H, Kumar K.
Bioorg Med Chem. 2015 Jun 1;23(11):2614-20. 
doi: 10.1016/j.bmc.2015.01.019 . Epub 2015 Jan 17.

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13 January 2015

Branching cascades provide access to two amino-oxazoline compound libraries.

Murali A, Medda F, Winkler M, Giordanetto F, Kumar K. 
Bioorg Med Chem. 2015 Jun 1;23(11):2656-65. 
doi: 10.1016/j.bmc.2015.01.009. Epub 2015 Jan 13.

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09 January 2015

The European Lead Factory – An experiment in collaborative drug discovery

Laverty HG, Orrling KM, Giordanetto F, Poinot M, Ottow E, Rijnders TW, Tzalis D, Jaroch S
Journal of Medicines Development Sciences 1.1 (2015).
doi: 10.18063/JMDS.2015.01.009

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29 December 2014

Synthesis and functionalization of bicyclic N,O-acetal scaffolds from furfural.

van der Pijl F, van Delft FL, Rutjes FP. 
Bioorg Med Chem. 2015 Jun 1;23(11):2721-9.
doi: 10.1016/j.bmc.2014.12.045. Epub 2014 Dec 29.

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29 December 2014

Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries

Craven P, Aimon A, Dow M, Fleury-Bregeot N, Guilleux R, Morgentin R, Roche D, Kalliokoski T, Foster R, Marsden SP, Nelson A. 
Bioorg Med Chem. 2015 Jun 1;23(11):2629-35. 
doi: 10.1016/j.bmc.2014.12.048 . Epub 2014 Dec 29.

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29 December 2014

Combining two-directional synthesis and tandem reactions. Part 21: Exploitation of a dimeric macrocycle for chain terminus differentiation and synthesis of an sp(3)-rich library.

Storr TE, Cully SJ, Rawling MJ, Lewis W, Hamza D, Jones G, Stockman RA.
Bioorg Med Chem. 2015 Jun 1;23(11):2621-8.
doi: 10.1016/j.bmc.2014.12.050 . Epub 2014 Dec 29.

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20 December 2014

MCR synthesis of a tetracyclic tetrazole scaffold.

Patil P, Khoury K, Herdtweck E, Dömling A. 
Bioorg Med Chem. 2015 Jun 1;23(11):2699-715. 
doi: 10.1016/j.bmc.2014.12.021. Epub 2014 Dec 20.

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17 November 2014

Concise Synthesis of Tetrazole–Ketopiperazines by Two Consecutive Ugi Reactions

Zarganes-Tzitzikas T, Patil P, Khoury K, Herdtweck E and Dömling A.
European Journal of Organic Chemistry Online; 
doi: 10.1002/ejoc.201403401. 17 November 2014

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29 October 2014

A Universal Isocyanide for Diverse Heterocycle Syntheses

Pravin Patil, Kareem Khoury, Eberhardt Herdtweck, and Alexander Dömling
Organic Letters 2014, 16 (21), pp 5736–5739
doi: 10.1021/ol5024882

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