Publications

This is a non exhaustive list of publications related to ELF work published in scientific journals. Please contact the programme office if you miss a relevant publication. 
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03 February 2015

Design and synthesis of 1,1-disubstituted-1-silacycloalkane-based compound libraries.

Ortega R, Sanchez-Quesada J, Lorenz C, Dolega G, Karawajczyk A, Sanz M, Showell G, Giordanetto F. 
Bioorg Med Chem. 2015 Jun 1;23(11):2716-20. 
doi: 10.1016/j.bmc.2015.01.046. Epub 2015 Feb 3.

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31 January 2015

Synthesis of 1,4,5 trisubstituted γ-lactams via a 3-component cascade reaction

Petersen MÅ, Mortensen MA, Cohrt AE, Petersen R, Wu P, Fleury-Brégeot N, Morgentin R, Lardy C, Nielsen TE, Clausen MH.
Bioorg Med Chem. 2015 Jun 1;23(11):2695-8. 
doi: 10.1016/j.bmc.2015.01.041. Epub 2015 Jan 31.

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31 January 2015

Cyclopentitol as a scaffold for a natural product-like compound library for drug discovery.

Padwal JD, Filippov DV, Narhe BD, Aertssen S, Beuving RJ, Benningshof JC, van der Marel GA, Overkleeft HS, van der Stelt M.
Bioorg Med Chem. 2015 Jun 1;23(11):2650-5. 
doi: 10.1016/j.bmc.2015.01.040. Epub 2015 Jan 31.

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31 January 2015

Synthesis of hexahydropyrrolo[2,1-a]isoquinoline compound libraries through a Pictet-Spengler cyclization/metal-catalyzed cross coupling/amidation sequence

Petersen R, Cohrt AE, Petersen MÅ, Wu P, Clausen MH, Nielsen TE.
Bioorg Med Chem. 2015 Jun 1;23(11):2646-9. 
doi: 10.1016/j.bmc.2015.01.039. Epub 2015 Jan 31.

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17 January 2015

Stereoselective synthesis of a natural product inspired tetrahydroindolo[2,3-a]-quinolizine compound library.

Sankar MG, Mantilli L, Bull J, Giordanetto F, Bauer JO, Strohmann C, Waldmann H, Kumar K.
Bioorg Med Chem. 2015 Jun 1;23(11):2614-20. 
doi: 10.1016/j.bmc.2015.01.019 . Epub 2015 Jan 17.

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13 January 2015

Branching cascades provide access to two amino-oxazoline compound libraries.

Murali A, Medda F, Winkler M, Giordanetto F, Kumar K. 
Bioorg Med Chem. 2015 Jun 1;23(11):2656-65. 
doi: 10.1016/j.bmc.2015.01.009. Epub 2015 Jan 13.

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09 January 2015

The European Lead Factory – An experiment in collaborative drug discovery

Laverty HG, Orrling KM, Giordanetto F, Poinot M, Ottow E, Rijnders TW, Tzalis D, Jaroch S
Journal of Medicines Development Sciences 1.1 (2015).
doi: 10.18063/JMDS.2015.01.009

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29 December 2014

Synthesis and functionalization of bicyclic N,O-acetal scaffolds from furfural.

van der Pijl F, van Delft FL, Rutjes FP. 
Bioorg Med Chem. 2015 Jun 1;23(11):2721-9.
doi: 10.1016/j.bmc.2014.12.045. Epub 2014 Dec 29.

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29 December 2014

Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries

Craven P, Aimon A, Dow M, Fleury-Bregeot N, Guilleux R, Morgentin R, Roche D, Kalliokoski T, Foster R, Marsden SP, Nelson A. 
Bioorg Med Chem. 2015 Jun 1;23(11):2629-35. 
doi: 10.1016/j.bmc.2014.12.048 . Epub 2014 Dec 29.

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29 December 2014

Combining two-directional synthesis and tandem reactions. Part 21: Exploitation of a dimeric macrocycle for chain terminus differentiation and synthesis of an sp(3)-rich library.

Storr TE, Cully SJ, Rawling MJ, Lewis W, Hamza D, Jones G, Stockman RA.
Bioorg Med Chem. 2015 Jun 1;23(11):2621-8.
doi: 10.1016/j.bmc.2014.12.050 . Epub 2014 Dec 29.

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