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March webinar: High Content Screening at the European Lead Factory
Phenotypic screening is a powerful approach to identifying novel chemical starting points for drug discovery. It uses cell-based assays and advanced data analytics to develop quantitative fingerprints that can uncover new drug targets and pathways underpinning disease-related biology.
High Content Screening (HCS) is one of the phenotypic screening approaches offered by the European Lead Factory (ELF) and in our next ELF webinar, taking place on 11 March, we will introduce you to HCS and explain how it can add value to your research.
What is HCS and what can you hope to get out of this session?
HCS is performed on cells or tissues grown in vitro, and often combines substantial automation, big data handling, and customised analysis workflows running on high performance computing systems. Like High Throughput Screening (HTS), HCS may focus on a specific target, but usually involves assays and reporters that provide additional information on cytotoxicity and other secondary effects. It can also be used in a target-agnostic approach, where an assay phenotype is linked to a disease state, and changes in that state are assayed.
Our keynote speaker for the session is Professor Jason Swedlow, head of the National Phenotypic Screening Centre (NPSC) at the University of Dundee – one of the European Lead Factory’s academic partners. Jason and colleagues from NPSC will showcase the capabilities for HCS assays that are available within the European Lead Factory. They will also provide useful tips (including the assay requirements) and tricks to get the most out of a HCS at the European Lead Factory.
The webinar forms part of a series of ELF online meetings held once a month to learn, share, and stay connected. Attendees will be introduced to the European Lead Factory and find out how to collaborate with the consortium to give their drug discovery programmes a major boost.
The event will take place via Microsoft Teams on Thursday 11 March from 11:00-12:00 (CET). Discussions with the audience will form a key part of the webinar and time will be made available for questions and answers.
We look forward to connecting with you online. Registration is free via this link.