Publications

Publication
16.11.2017
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Microwave-assisted Diastereoselective Two-step Three-component Synthesis for Rapid Access to Drug-like Libraries of Substituted 3-Amino-β-lactams

Guido V. Janssen, Joyce A.C. van den Heuvel, Rik P. Megens, Jorg C.J. Benningshof, Huib Ovaa
Bioorganic & Medicinal Chemistry (2017) 14066
doi: https://doi.org/10.1016/j.bmc.2017.11.014 Open Access

Publication
01.10.2017
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Piperidine and octahydropyrano[3,4-c]pyridine scaffolds for drug-like molecular libraries of the European Lead Factory

B.D. Narhe, A.C. Breman, J. Padwal, D.A.L. Vandenput, J.M. Scheidt, J.C.J. Benningshof, G.A. van der Marel, H.S. Overkleeft, M. van der Stelt, D.V. Filippov
Bioorganic & Medicinal Chemistry 2017; 25:5160–5170
doi: 10.1016/j.bmc.2017.07.016 2017 October 1

Publication
13.06.2017
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Reference Module in Chemistry, Molecular Sciences and Chemical Engineering

F. Giordanetto, P. Jones, A. Nelson, J. Benningshof, G. Müller, A. Pannifer and D.Tzalis
Comprehensive Medicinal Chemistry III 2017, 505-519
doi:10.1016/B978-0-12-409547-2.12303-0 2017 June 13

Publication
05.06.2017
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Sulfur-Switch Ugi-Reaction For Macrocyclic Disulfide-Bridged Peptidomimetics

T. M. Vishwanatha, E. Bergamaschi and A. Dömling
Organic Letters Article ASAP 2017
doi: 10.1021/acs.orglett.7b01324 2017 June 5

Publication
18.05.2017
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Highly Stereoselective Synthesis of a Compound Collection Based on the Bicyclic Scaffolds of Natural Products

M. Annamalai, S. Hristeva, M. Bielska, R. Ortega and K. Kumar
Molecules 2017, 22, 827
doi: 10.3390/molecules22050827 2017 May 18

Publication
03.03.2017
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N-Hydroxyimide Ugi Reaction toward α-Hydrazino Amides

A.L. Chandgude and A. Dömling
Org Lett. 2017 Mar 3;19(5):1228-1231
doi: 10.1021/acs.orglett.7b00205 2017 March 3

Publication
27.02.2017
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Ammonia-Promoted One-Pot Tetrazolopiperidinone Synthesis by Ugi Reaction

P. Patil, K. Kurpiewska, J. Kalinowska-Tłusćik and A. Dömling
ACS Comb. Sci. 2017, 19, 343−350
doi: 10.1021/acscombsci.7b00033 2017 February 27

Publication
24.02.2017
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Synthesis of 4-aminotetrahydropyran scaffolds for drug discovery

A. Nortcliffe, G.D.S. Milne, D. Hamza and C.J. Moody 
Bioorganic & Medicinal Chemistry 25 (2017) 2218–2225
doi: 10.1016/j.bmc.2017.02.039 2017 February 24

Publication
09.02.2017
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Two Cycles with One Catch: Hydrazine in Ugi 4-CR and Its Postcyclizations

Y. Wang, P. Patil, K. Kurpiewska, J. Kalinowska-Tluscik and A. Dömling
ACS Comb Sci. 2017 Mar 13;19(3):193-198
doi: 10.1021/acscombsci.7b00009 2017 February 9

Publication
19.01.2017
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The European Lead Factory: A Blueprint for Public–Private Partnerships in Early Drug Discovery

A. Karawajczyk, K.M. Orrling, J.B.S. de Vlieger, T. Rijnders and D. Tzalis
Front. Med. 2017 3 (75)
doi: 10.3389/fmed.2016.00075 2017 January 19

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