Publications

This is a non exhaustive list of publications related to ELF work published in scientific journals. Please contact the programme office if you miss a relevant publication. 
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22 February 2018

Design and synthesis of a fragment set based on twisted bicyclic lactams

H. Hassan, S.P. Marsden, A. Nelson 
Bioorganic & Medicinal Chemistry 2018;26(11):3030-3033
doi: 10.1016/j.bmc.2018.02.027 2018 February 22

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20 February 2018

Using Microscale Thermophoresis to Characterize Hits from High-Throughput Screening: A European Lead Factory Perspective

Julie M. Rainard, George C. Pandarakalam, Stuart P. McElroy 
SLAS Discovery 2018;23(3):225–241
doi: http://journals.sagepub.com/doi/10.1177/2472555217744728 2018 February 20, Open Access

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19 February 2018

Synthesis of Highly Substituted Imidazole Uracil Containing Molecules via Ugi-4CR and Passerini-3CR

Rudrakshula Madhavachary, Tryfon Zarganes-Tzitzikas, Pravin Patil, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Alexander Dömling
ACS Combinatorial Science 2018;20(4):192–196
doi: 10.1021/acscombsci.7b00145 2018 February 19

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15 February 2018

Densely functionalised spirocyclic oxetane-piperidine scaffolds for drug discovery

Gemma C. Geary, Andrew Nortcliffe, Christopher A. Pearce, Daniel Hamza, Geraint Jones, Christopher J. Moody
Bioorganic & Medicinal Chemistry 2018;26(4):791-797
doi: https://doi.org/10.1016/j.bmc.2017.12.012 2018 February 15

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12 January 2018

Two-Step Macrocycle Synthesis by Classical Ugi Reaction

Eman M. M. Abdelraheem, Samad Khaksar, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Shabnam Shaabani, Alexander Dömling
Journal of Organic Chemistry 2018;83(3):1441–1447
doi: 10.1021/acs.joc.7b02984 2018 January 12
 

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10 January 2018

Concise synthesis of macrocycles by multicomponent reactions

Eman M. M. Abdelraheem, Samad Khaksar, Alexander Dömling
Synthesis 2018;50(5):1027-1038
doi: 10.1055/s-0036-1590946 2018 January 10

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07 December 2017

Library-to-Library Synthesis of Highly Substituted α-Aminomethyl Tetrazoles via Ugi Reaction

Pravin Patil, Bhupendra Mishra, Gitanjali Sheombarsing, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Alexander Dömling
ACS Combinatorial Science 2018;20(2):70–74
doi: 10.1021/acscombsci.7b00137 2017 December 7

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16 November 2017

Microwave-assisted Diastereoselective Two-step Three-component Synthesis for Rapid Access to Drug-like Libraries of Substituted 3-Amino-β-lactams

Guido V. Janssen, Joyce A.C. van den Heuvel, Rik P. Megens, Jorg C.J. Benningshof, Huib Ovaa
Bioorganic & Medicinal Chemistry (2017) 14066
doi: https://doi.org/10.1016/j.bmc.2017.11.014 Open Access

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30 October 2017

Ugi Multicomponent Reaction Based Synthesis of Medium-Sized Rings

Eman M. M. Abdelraheem, Rudrakshula Madhavachary, Arianna Rossetti, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Shabnam Shaabani, Alexander Dömling
Organic Letters 2017;19(22):6176–6179
doi: 10.1021/acs.orglett.7b03094 2017 October 30

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26 October 2017

Diastereoselective One Pot Five-Component Reaction toward 4-(Tetrazole)-1,3-Oxazinanes

Ajay L. Chandgude, Daniele Narducci, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścikb, Alexander Dömling
RSC Advances 2017;79:49995-49998 
doi: 10.1039/C7RA07392E 2017 October 26, Open Access

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