Publications

This is a non exhaustive list of publications related to ELF work published in scientific journals. Please contact the programme office if you miss a relevant publication. 

Publication
Share this article
15 February 2018

Densely functionalised spirocyclic oxetane-piperidine scaffolds for drug discovery

Gemma C. Geary, Andrew Nortcliffe, Christopher A. Pearce, Daniel Hamza, Geraint Jones, Christopher J. Moody
Bioorganic & Medicinal Chemistry 2018;26(4):791-797
doi: https://doi.org/10.1016/j.bmc.2017.12.012 2018 February 15

Publication
Share this article
12 January 2018

Two-Step Macrocycle Synthesis by Classical Ugi Reaction

Eman M. M. Abdelraheem, Samad Khaksar, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Shabnam Shaabani, Alexander Dömling
Journal of Organic Chemistry 2018;83(3):1441–1447
doi: 10.1021/acs.joc.7b02984 2018 January 12
 

Publication
Share this article
10 January 2018

Concise synthesis of macrocycles by multicomponent reactions

Eman M. M. Abdelraheem, Samad Khaksar, Alexander Dömling
Synthesis 2018;50(5):1027-1038
doi: 10.1055/s-0036-1590946 2018 January 10

Publication
Share this article
07 December 2017

Library-to-Library Synthesis of Highly Substituted α-Aminomethyl Tetrazoles via Ugi Reaction

Pravin Patil, Bhupendra Mishra, Gitanjali Sheombarsing, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Alexander Dömling
ACS Combinatorial Science 2018;20(2):70–74
doi: 10.1021/acscombsci.7b00137 2017 December 7

Publication
Share this article
16 November 2017

Microwave-assisted Diastereoselective Two-step Three-component Synthesis for Rapid Access to Drug-like Libraries of Substituted 3-Amino-β-lactams

Guido V. Janssen, Joyce A.C. van den Heuvel, Rik P. Megens, Jorg C.J. Benningshof, Huib Ovaa
Bioorganic & Medicinal Chemistry (2017) 14066
doi: https://doi.org/10.1016/j.bmc.2017.11.014 Open Access

Publication
Share this article
30 October 2017

Ugi Multicomponent Reaction Based Synthesis of Medium-Sized Rings

Eman M. M. Abdelraheem, Rudrakshula Madhavachary, Arianna Rossetti, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Shabnam Shaabani, Alexander Dömling
Organic Letters 2017;19(22):6176–6179
doi: 10.1021/acs.orglett.7b03094 2017 October 30

Publication
Share this article
26 October 2017

Diastereoselective One Pot Five-Component Reaction toward 4-(Tetrazole)-1,3-Oxazinanes

Ajay L. Chandgude, Daniele Narducci, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścikb, Alexander Dömling
RSC Advances 2017;79:49995-49998 
doi: 10.1039/C7RA07392E 2017 October 26, Open Access

Publication
Share this article
06 October 2017

Synthesis and Demonstration of the Biological Relevance of sp3-rich Scaffolds Distantly Related to Natural Product Frameworks

Daniel J. Foley, Philip G. E. Craven, Patrick M. Collins, Richard G. Doveston, Anthony Aimon, Romain Talon, Ian Churcher, Frank von Delft, Stephen P. Marsden, Adam Nelson
Chem. Eur. J. 2017;23,15227
doi: https://doi.org/10.1002/chem.201704169 2017 October 10, Open Access

Publication
Share this article
05 October 2017

Privileged heterocycles: bioactivity and synthesis of 1,9-diazaspiro 5.5 undecane-containing compounds

Daniel Blanco-Ania, Rik Heus, Floris P.J.T. Rutjes
Chemistry of Heterocyclic Compounds 2017;53(8):827–845
doi: https://doi.org/10.1007/s1059 2017 October 5

Publication
Share this article
01 October 2017

Piperidine and octahydropyrano[3,4-c]pyridine scaffolds for drug-like molecular libraries of the European Lead Factory

B.D. Narhe, A.C. Breman, J. Padwal, D.A.L. Vandenput, J.M. Scheidt, J.C.J. Benningshof, G.A. van der Marel, H.S. Overkleeft, M. van der Stelt, D.V. Filippov
Bioorganic & Medicinal Chemistry 2017; 25:5160–5170
doi: 10.1016/j.bmc.2017.07.016 2017 October 1

Pages